In the Spring semester of 2000, a group of women attending Ramapo College went before the college's Panhellenic Council to present their reasons for wanting to install another Greek Organization on campus. These women were constantly targeted and faced many hardships, but remained united and determined to bring a fourth Panhellenic sorority to the school. Finally, their request was approved and they began preparing to bring on a new sorority.
Then during the Fall 2000 semester, members of the interest group met with a representative from Sigma Sigma Sigma to learn about the colonization process. A group of twenty-five women came together to start colonization that semester, and in February of 2001, they began colonization at Ramapo College, participating in the formal recruitment process along with the other three sororities. Through recruitment, the group brought in another ten women, who would eventually make up the thirty-five charter members of Eta Nu.
On October 20, 2001, national officers and other Tri Sigma dignitaries converged on Ramapo College marking the official chartering of Eta Nu.